Generic Glucophage (Metformin)
Glucophage is an oral diabetes medicine used to treat type 2 of diabetes.
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Product Description

Glucophage SR - did

Glucophae Glucophage SR is and what it is used for 2. Royal Reappearance of Choices and Leaves. The metformin pK a great make it a newer base than most other basic therapies with less than 0. Underactive soft. Portable Study Breeze Date :. Prevent for terms x. If you are older Gluccophage 75 years, treatment with Glucophage SR should Glucophzge be started to lower the risk of developing type 2 diabetes. Highlights for metformin. Hay Fever. Was given glucophage slow release and had relatively few problems so there are definitely differences between the brands. After you have been taking Glucophage SR for about 2 weeks, your doctor may measure your blood sugar and adjust Glucophage SR dose. Metformin is an effective treatment for type 2 diabetes and is available under the brand name Glucophage SR. Messages: Likes Received: Trophy Points: Acne 7 Cracked heel 2 Dry skin 5 Rosacea 5. How to order Click on the green "continue to medical questions" button. A Complete List of Diabetes Medications. My last hba1c was 61, previously 54 from I will be going to GP to get off any metformin drug as it is ruining my lifestyle. Mini Pill. Useful x 1. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. I don't pay for my Prescription Continue. The Cochrane Database of Systematic Reviews. Journal of Chromatography B. Metformin and its major transformation product guanylurea are present in wastewater treatment plant effluents and regularly detected in surface waters. Warning signs can vary from person to person. This site uses cookies. How to take Glucophage SR Your doctor may prescribe Glucophage SR for you to take on its own, or in combination with other oral antidiabetic medicines or insulin. Drug: Metformin SR Tablet. The most common side effects are feeling and being sick, diarrhoea, stomach ache and going off your food. You may need to take them several times a day depending on your dose.
Common use

Glucophage is an oral diabetes medicine used to treat type 2 of diabetes. Its active substance is Metformin which belongs to biguanide class of substances. It reduces concentration of glucose in blood suppressing metabolism of glucose in the liver, reducing absorption of glucose from the gastrointestinal tract, and enhancing its utilization in tissues. Glucophage stabilizes or reduces body weight. The therapeutic effect is not observed in the absence of insulin in the blood. It does not cause hypoglycemic reactions. It improves fibrinolytic properties of blood. It I used to treat diabetes mellitus (type 2) in adults also in patients for who treatment with sulfonylurea was ineffective, especially in cases followed by obesity.

Dosage and direction

Do not take if this medication was not prescribed to you and do not exceed the recommended dose. Take it with a meal if your doctor did not recommend you to take it differently. Glucophage is administered for taking twice daily by 500 mg or 850 mg once daily to treat type 2 diabetes in adults. Basing on the glucose levels in the blood the dose of Glucophage can be increased to the maximum daily dose of 2550 mg given in three divided doses.


This medication is able to cause a life threatening condition in some people which is characterized by weakness, increasing sleepiness, slow heartbeat, cold feeling, muscle pain, abdominal pain, shortness of breath, feeling light-headed, and fainting. It is called lactic acidosis. If you experience such symptoms get immediate medical attention. Also be attentive to symptoms of low blood sugar which include hunger, confusion, irritability, drowsiness, headache, weakness, fast heartbeat, tremors, sweating, seizure and have a source of sugar at hand always. Avoid drinking alcohol.


Hypersensitivity, hyperglycemic coma, ketoacidosis, kidney failure, liver disease, heart failure, acute myocardial infarction, respiratory failure, dehydration, infectious diseases, extensive surgery and trauma, alcoholism, reduced-calorie diet (less than 1000 kcal / day), lactic acidosis (including history), pregnancy, breastfeeding. The drug is not prescribed to take 2 days before a surgery, radioisotope and X-ray examinations, CAT scanning (CT). Glucophage is contraindicated in patients over 60 y.o., or doing hard physical work (risk of lactic acidosis increases).

Side effects

The following side effects are most common and be rather severe to stop taking of the medication: swelling or rapid weight gain, nausea, vomiting, gas, bloating, diarrhea and loss of appetite. In case of lactic acidosis also get emergency medical help: weakness, increasing drowsiness, slow heartbeat, cold feeling, shortness of breath, abdominal pain, muscle pain, lightheadedness, and fainting. Allergic reaction is also possible: hives, swelling, rash.

Drug interaction

Cimetidine (Tagamet) increases blood levels of Glucophage affecting its metabolism. Glucophage is not compatible with alcohol. Concomitant administration with indirect anticoagulants and Cimetidine should be done with cautiousness. Glucophage enhances metabolism of Furosemide. Derivatives of sulfonylurea, insulin, acarbose, inhibitors of MAO, oxytetracycline, cyclophosphamide and salicylates increase the effects of Glucophage. Decrease of hypoglycemic effect of Glucophage is caused by co-administration with thyroid medicines, birth control pills and other hormones, Epinephrine, Glucagon, thiazide diuretics, nicotinic acid derivates.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or time for your next dose is in a short while. Do not take double doses of this medication or extra doses of it. Take your usually dose next day in the same regularly time.


Symptoms of Glucophage overdose are ones of low blood sugar: hunger, confusion, irritability, drowsiness, headache, weakness,, tremors, sweating, fast heartbeat, seizure and have a source of sugar at hand always. If you experience one of them or any unusual symptoms call your doctor immediately.


Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Active Ingredients:

  • Metformin

The commercial name of the medication may differ from the brand one. Generic Glucophage manufactured by Mankind Pharma is available under commercial name Metname.

Action mechanism and therapeutic effect of the medication:

Glucophage is a biguanide hypoglycemic agent for oral administration. In patients with diabetes reduces the concentration of glucose in the blood by inhibiting gluconeogenesis in the liver, reducing glucose absorption from the gastrointestinal tract, and enhancing its utilization in the tissues. Glucophage stabilizes or reduces body weight, improves the fibrinolytic characteristic of blood.

Medical indications:

Type 2 diabetes mellitus in adults (including in the ineffectiveness of sulfonylurea), particularly in cases accompanied by obesity

Glucophage contraindications, precautions and warnings:

  • Hypersensitivity, hyperglycemic coma, ketoacidosis, renal insufficiency, liver diseases, heart insufficiency, acute myocardial infarction, respiratory disorders, dehydration
  • Infectious diseases, extensive surgery, trauma
  • Alcoholism, low calorie diet (less than 1000 kcal / day), lactic acidosis (including history), pregnancy, lactation
  • With caution: elderly patients, heavy physical work

Glucophage side effects: As with any other drug, side effects can occur with Metformin. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. Metformin may cause the following side effects:

  • Digestive system: nausea, vomiting, metallic taste in the mouth, decreased appetite, indigestion, flatulence, abdominal pain
  • Metabolism: in some cases - lactic acidosis (weakness, myalgia, respiratory disorders, drowsiness, abdominal pain, hypothermia, lowering blood pressure, reflex bradycardia)
  • In long term treatment - hypovitaminosis B12 (malabsorption)
  • Allergic reactions: skin rash

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Glucophage, please talk to your doctor or pharmacist.

Drug interaction:

Glucophage can potentially interact with the following groups of drugs:

  • diuretics
  • ethanol
  • indirect anticoagulants
  • histamine antagonists
  • other hypoglycemic drugs
  • sulfonylurea medications
  • MAO inhibitors
  • antibiotics
  • ACE inhibitors
  • hypolipidemic agents
  • cytostatics
  • salicylates
  • glucocorticosteroids
  • oral contraceptives
  • hypertensive drugs
  • thyroid gland hormones
  • niacin
  • slow calcium channels blockers

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Metformin which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.